Type 1 diabetes:
• Polyuria, polydipsia, and weight loss associated with random plasma glucose = 200 mg/dL. • Plasma glucose of 126 mg/dL or higher after an overnight fast, documented on more than one occasion. • Ketonemia, ketonuria, or both. • Islet autoantibodies are frequently present.
Type 2 diabetes:
• Most patients are over 40 years of age and obese. • Polyuria and polydipsia. Ketonuria and weight loss generally are uncommon at time of diagnosis. Candidal vaginitis in women may be an initial manifestation. Many patients have few or no symptoms. • Plasma glucose of 126 mg/dL or higher after an overnight fast on more than one occasion. After 75 g oral glucose, diagnostic values are 200 mg/dL or more 2 hours after the oral glucose. • Hypertension, dyslipidemia, and atherosclerosis are often associated.
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